DISTINCT MOTOR IMPAIRMENTS OF DOPAMINE D1 AND D2 RECEPTOR KNOCKOUT MICE REVEALED BY THREE TYPES OF MOTOR BEHAVIOR

Distinct motor impairments of dopamine D1 and D2 receptor knockout mice revealed by three types of motor behavior

Both D1R and D2R knock out (KO) mice of the major dopamine receptors show significant motor impairments.However, there are some discrepant reports, which may be due to the differences in genetic background and experimental procedures.In addition, only few studies directly compared the motor performance of D1R and D2R KO mice.In this paper, we exami

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Ethical criteria when a (potential) perpetrator asks a human rights organization to defend their case based on the forensic documentation of alleged torture. How shall we proceed?

Objective Discuss the ethical dilemma of perpetrators requesting clinical evaluations intended to prove persecution or torture.The discussion is organized around three real cases.Method We present three cases of plausible perpetra- tors, partially amended to protect anonymity.The paper presents a review of the complex ethical challenges that the di

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